Kalpesh Chokashi
B. Pharm ., M. Tech. BPT (Currently Ph. D. Student)
Email: ce07kp.chokashi@ictmumbai.edu.in
| Education Details | ||
Course |
Institute/University |
Year of Passing |
| B. Pharm | University of Pune | 2005 |
| M. Tech. Bio Process Technology |
University Institute of Chemical Technology, UICT, Mumbai | 2007 |
| Ph. D. Tech. Bio Process Technology |
University Institute of Chemical Technology, UICT, Mumbai | - |
Abstract of Ph. D. Thesis:
ADVANCED DRYING TECHNIQUES FOR BIOLOGICAL PRODUCTS
A wide choice of biotechnological products indicates that it is possible to use various methods to dry them. Particular attention is given to its sensitivity and qualitative changes due to dewatering at elevated temperature. However, taking into account thermo sensitivity and risk of many qualitative changes in these products, some process conditions needed to be observed vary closely for example, temperature and moisture content of the product and so on. In the case drying of biotechnological, food, and pharmaceutical products, the temperature and pressure conditions are maintained below the triple point of the solution to be dried. Freeze dryers are most commonly used in the bio-industry for the drying of biopolymers, therapeutic proteins and vaccines. In freeze drying, as the moisture removal is done by sublimation, there is every possibility of retaining the original shape and structure of the material. The spray drying method is widely used for heat sensitive materials such as biopolymers, suspension of antibiotics, fodder yeast, amino acids, and enzymes. Heat pump drying is again one of the novel techniques for drying of biological products. Many researchers have successfully applied atmospheric freeze drying using heat pumps to dry number of heat sensitive products. The process involves blowing of highly dehumidified air over a frozen material. The product qualities obtained using heat pump dryer is comparable to the freeze dried products. Dehumidified air can be used for spray drying to lower the chances of damage to the heat sensitive products during spray drying. There are possibilities of using closed loop heat pump assisted spray dryer using nitrogen as a drying media to minimize the chances of oxidation.